Biodegradation of venlafaxine (LB289)

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Venlafaxine and reversible blepharoedema.

The newer antidepressant venlafaxine is known to cause dilutional hyponatraemia, but to our knowledge no reports on localized oedemas in the absence of electrolyte disturbances are available. We present a case in which venlafaxine caused reversible blepharoedema in an otherwise physically healthy patient. Ms. M., a 25-yr-old women, suffered from schizoaffective disorder since being 23 years old...

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Venlafaxine besylate monohydrate

The title compound {systematic name: [2-(1-hydroxycyclohexyl)-2-(4-methoxyphenyl)ethyl]dimethylazanium benzene-sulfonate monohydrate}, C17H28NO2 (+)·C6H5O3S(-)·H2O, is a besylate salt hydrate of the anti-depressant drug venlafaxine. In the crystal, besylate anions and water mol-ecules self-assemble, forming hydrogen-bonded dimers linked around inversion centers, with graph set R 4 (4)(6). The c...

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ژورنال

عنوان ژورنال: The FASEB Journal

سال: 2014

ISSN: 0892-6638,1530-6860

DOI: 10.1096/fasebj.28.1_supplement.lb289